Cyclopropanecarboxylic acid, 1-(4-boronophenyl)-
1-(4-Boronophenyl)cyclopropanecarboxylic acid
CAS: 1159489-46-9
Molecular Formula: C10H11BO4
Cyclopropanecarboxylic acid, 1-(4-boronophenyl)- - Names and Identifiers
Cyclopropanecarboxylic acid, 1-(4-boronophenyl)- - Physico-chemical Properties
| Molecular Formula | C10H11BO4 |
| Molar Mass | 206 |
| Density | 1.38±0.1 g/cm3(Predicted) |
| Boling Point | 445.1±55.0 °C(Predicted) |
| pKa | 4.23±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD09037835 |
Cyclopropanecarboxylic acid, 1-(4-boronophenyl)- - Introduction
1-(4-Boronophenyl)cyclopropanecarboxylic acid is an organic compound containing a boron group. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystal or crystalline powder
-Molecular formula: C10H9BO2
-Molecular weight: 164.99g/mol
-Melting point: about 130-133°C
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and dimethyl formamide
Use:
- 1-(4-Boronophenyl)cyclopropanecarboxylic acid is mainly used for C- C bond formation reactions in organic synthesis. It can be used as a catalyst precursor for catalytic asymmetric hydrogenation reactions and asymmetric carbon-carbon bond formation reactions.
-This compound is also commonly used in the fields of pharmaceutical synthesis, materials science and organic optoelectronic devices.
Preparation Method:
The preparation of -1-(4-Boronophenyl)cyclopropanecarboxylic acid usually involves a multi-step reaction. One common method is to first synthesize phenylcyclopropanoyl chloride and then react with a borophenyl Grignard reagent to obtain the desired product.
Safety Information:
-The toxicity and safety data of this compound are limited, so appropriate protective measures should be taken when handling.
-In case of contact with skin, eyes or inhalation of the compound, rinse immediately with plenty of water and seek medical assistance.
-Avoid inhaling dust and skin contact during operation.
-Operate in a well-ventilated area and wear appropriate personal protective equipment, such as gloves, goggles and protective clothing.
-During use and storage, safe operating procedures and correct laboratory practices should be observed.
Nature:
-Appearance: White crystal or crystalline powder
-Molecular formula: C10H9BO2
-Molecular weight: 164.99g/mol
-Melting point: about 130-133°C
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and dimethyl formamide
Use:
- 1-(4-Boronophenyl)cyclopropanecarboxylic acid is mainly used for C- C bond formation reactions in organic synthesis. It can be used as a catalyst precursor for catalytic asymmetric hydrogenation reactions and asymmetric carbon-carbon bond formation reactions.
-This compound is also commonly used in the fields of pharmaceutical synthesis, materials science and organic optoelectronic devices.
Preparation Method:
The preparation of -1-(4-Boronophenyl)cyclopropanecarboxylic acid usually involves a multi-step reaction. One common method is to first synthesize phenylcyclopropanoyl chloride and then react with a borophenyl Grignard reagent to obtain the desired product.
Safety Information:
-The toxicity and safety data of this compound are limited, so appropriate protective measures should be taken when handling.
-In case of contact with skin, eyes or inhalation of the compound, rinse immediately with plenty of water and seek medical assistance.
-Avoid inhaling dust and skin contact during operation.
-Operate in a well-ventilated area and wear appropriate personal protective equipment, such as gloves, goggles and protective clothing.
-During use and storage, safe operating procedures and correct laboratory practices should be observed.
Last Update：2024-04-09 20:49:11
